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Clinoril

( sulindac )

 

150 mg, 200 mg bright yellow, hexagon-shaped tablets

 

Purpose

To reduce inflammation; to reduce pain.

 

Indications

For anti-inflammatory action and pain relief.

 

Dosage

One 150 mg tablet twice a day. This drug also comes in a 200 mg tablet, and dosage may be increased to 200 mg twice a day if needed. Maximum recommended dose is 400 mg a day.

 

Side effects

Gastrointestinal side effects, with irritation of the stomach lining, are the most common, and include nausea, indigestion, and heartburn. Stomach pain has been reported in 10% of subjects, and nausea, diarrhea, constipation, headache, and rash in from 3% to 9%. Ringing in the ears, fluid retention, itching, and nervousness have been reported. Allergic reactions are rare. The use of aspirin in combination with this drug is not recommended by the manufacturer, since aspirin apparently decreases absorption from the intestine. Hospitalization for gastrointestinal bleeding occurs in about 1% of those taking full doses for one year.

 

Special hints

Sulindac has no particular advantages or disadvantages over the other anti-inflammatory agents, except that it may cause the minor kidney side effects less frequently and therefore is sometimes used for people with heart or kidney problems.

 

For stomach upset, take the pills after meals; skip a dose or two if necessary. Antacids may be used for gastrointestinal problems and may sometimes help. Check with your doctor if the distress continues. Maximum therapeutic effect is achieved after about six weeks of treatment, but you should be able to see a major effect in the first week if Clinoril is going to be a really good drug for you.

         
         

     

         

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