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Motrin

( ibuprofen; also called Advil and Nuprin )

 

300 mg round, white tablet

400 mg round, red-orange tablet

600 mg oval, peach tablet

800 mg apricot, capsule-shaped tablet

 

Motrin is a brand name for the drug ibuprofen. Advil and Nuprin contain smaller doses of ibuprofen and are available without a prescription, as is Motrin.

 

Purpose

To reduce inflammation; to reduce pain.

 

Indications

For anti-inflammatory action and pain relief

 

Dosage

One or two 400 mg tablets three times daily. Maximum daily recommended dosage is 2,400 mg, or six tablets.

 

Side effects

Gastrointestinal side effects, with irritation of the stomach lining, are the most common, and include nausea, indigestion, and heartburn. Allergic reactions are rare and the drug is generally well tolerated. A related to this drug. Here, the person experiences a headache, fever, and stiff neck, and examination of the spinal fluid shows an increase in the protein and cells. The syndrome resolves when the drug is stopped, but can come back again if the drug is given again. Occasionally, individuals may retain fluid with this medication. Hospitalization for gastrointestinal bleeding is seen in about 1% of those who take full doses of 2,400 mg or more per day for one year.

 

Special hints

Motrin is not consistently useful for the treatment of rheumatoid arthritis. Overall, many doctors are beginning to feel that it is one of the weaker therapeutic agents in this group. If you are not getting enough relief from it, you may wish to discuss a change in medication with your doctor. Avoidance of aspirin and other medications while taking Motrin is advisable but not essential. It is absorbed reasonably well even on a full stomach, so if you have problems with irritation of the stomach take the drug after an antacid or after a meal. Maximum effect is achieved after about six weeks of treatment, but you should be able to see a major effect in the first week if it is going to be a really good drug for you.

 

Over-the-counter Ibuprofen

The US Food and Drug Administration allows the sale of ibuprofen without a prescription in a smaller, 200 mg tablet size. The decision was made after careful review of many studies indicating that ibuprofen was at least as effective as two previously available drugs, aspirin and acetaminophen, for relieving minor pain and possibly less toxic than aspirin. Advil, Nuprin, and Motrin are trade names for over-the-counter ibuprofen, and they are already heavily advertised and heavily used. Ibuprofen is now also present in many different over-the-counter medications, including Midol.

 

What does this mean for the patient with arthritis ? Relatively little. Many arthritis patients need at least 2,400 mg of ibuprofen per day, and taking twelve Advil tablets a day rather than four to six Motrin is a bit of a nuisance. And it is hard to save money, since the cost per milligram is set so that it is about the same by prescription or over-the-counter. If you need anti-inflammatory doses of ibuprofen, you should be seeing your doctor every so often anyway, so do not use the availability of the product over the counter as an excuse to stay away from the doctor. Also, many health insurance plans will not pay for medication unless it is purchased by prescription. So, our recommendation remains that ibuprofen for arthritis be used on a prescription basis unless just an occasional tablet is required for pain.

         
         

     

         

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