( nabumetone )
500 mg oval-shaped, film-coated
750 mg oval-shaped, film-coated
To reduce inflammation; to reduce pain.
For anti-inflammatory action and
pain relief in patients with osteoarthritis and rheumatoid arthritis.
Therapy is usually initiated at a
dose of 1,000 mg daily, then adjusted, if needed, based on clinical
This is a new drug, and it has
been developed in part to minimize toxicity tot he stomach lining. Minor
stomach ulcers are less common with this drug than with most other NSAIDs
and occur approximately as often as with ibuprofen when misoprostol (
Cytotec ) is used to help protect the stomach. On the other hand, reduction
in major ulcers and in stomach bleeding have not yet been shown, and
experience with the drug is limited. Diarrhea is said to occur in 14% of
people taking this drug, heartburn in 13%, and abdominal pain in 12%. These
figures not very different from those of other NSAIDs.
Do not exceed 2,000 mg per day.
The lowest effective dose should be used if you are going to be taking the
drug for a while.