Each tablet contains:
Chlorpheniramine maleate 4mg
Chlorpheniramine maleate is an antihistamine that possesses anticholinergic
and sedative effects. It acts by occupying the 'receptive sites' on the
effector cells to the exclusion of the agonist without initiating a
It is indicated in allergic conditions responsive to antihistamines.
Side effects/Adverse reactions:
The most common side effect is sedation, varying from slight drowsiness to
deep sleep, and including inability to concentrate, lassitude, dizziness,
hypotension, muscular weakness and in co-ordination. Other side effects
include nausea, vomiting, diarrhoea, or constipation, colic and epigastric
pain, dryness of mouth, tightness of chest, heaviness and weakness of the
hands, 'ringing' in the ears, anorexia and nightmares.
Chlorpheniramine maleate may impair mental alertness required for the
performance of potentially hazardous activities such as driving a vehicle or
Chlorpheniramine maleate has an atropine-like action and is contraindicated
in patients with narrow-angle glaucoma, urinary retention, peptic ulcer,
during an asthmatic attack and in patients receiving MAO inhibitors.
Chlorpheniramine maleate interact with the anticonvulsant, phenytoin sodium
enhancing its effects.
Concomitant use of chlorpheniramine maleate with alcohol, tranquillizers and
sedatives may have an additive effect.
Use in Pregnancy and Lactation:
There are no adequate or well-controlled studies in pregnant women and this
drug should be used during pregnancy only if clearly needed. It should not
be used during pregnancy unless the potential benefits outweigh the
potential risks to the foetus.
Adults : 4 mg three to four times daily.
Children up to 1 year : 1 mg twice daily.
1 to 5 years : 1 to 2 mg three times daily.
6 to 12 years : 2 to 4 mg three to four times daily.
All doses are to be
taken after meals.
Symptoms and Treatment for overdosage:
Symptoms are as in 'Side effects/Adverse reactions'.
If the drug has been taken recently, the stomach should be emptied by
aspiration and lavage. The patient should be kept quiet to minimise the
excitation which occurs particularly in children. Convulsions and marked
central nervous system stimulation should preferably be treated with
diazepam or phenobarbitone intramuscularly, paraldehyde, thiopentone sodium
and chlorpromazine. Severe hypotension may require fluid replacement and
assisted respiration may be necessary.
Pack size: A bottle of 1000 tablets.
Blister pack: A box of 100 x 10 tablets per strip.
Storage conditions: Store at temperature 25°C. Protect from light.
Shelf-life: 5 years.
Description: Round, yellow, convex, plain tablet with "SW" debossed on one