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Allersin F
Each tablet contains:

Chlorpheniramine maleate    4mg

Pharmacology:
Chlorpheniramine maleate is an antihistamine that possesses anticholinergic and sedative effects. It acts by occupying the 'receptive sites' on the effector cells to the exclusion of the agonist without initiating a response.

Indications:
It is indicated in allergic conditions responsive to antihistamines.

Side effects/Adverse reactions:
The most common side effect is sedation, varying from slight drowsiness to deep sleep, and including inability to concentrate, lassitude, dizziness, hypotension, muscular weakness and in co-ordination. Other side effects include nausea, vomiting, diarrhoea, or constipation, colic and epigastric pain, dryness of mouth, tightness of chest, heaviness and weakness of the hands, 'ringing' in the ears, anorexia and nightmares.

Precautions/Warnings:
Chlorpheniramine maleate may impair mental alertness required for the performance of potentially hazardous activities such as driving a vehicle or operating machinery.

Contraindications:
Chlorpheniramine maleate has an atropine-like action and is contraindicated in patients with narrow-angle glaucoma, urinary retention, peptic ulcer, during an asthmatic attack and in patients receiving MAO inhibitors.

Drug Interactions:
Chlorpheniramine maleate interact with the anticonvulsant, phenytoin sodium enhancing its effects.


Concomitant use of chlorpheniramine maleate with alcohol, tranquillizers and sedatives may have an additive effect.

Use in Pregnancy and Lactation:
There are no adequate or well-controlled studies in pregnant women and this drug should be used during pregnancy only if clearly needed. It should not be used during pregnancy unless the potential benefits outweigh the potential risks to the foetus.


Dosage:
Adults : 4 mg three to four times daily.
Children up to 1 year : 1 mg twice daily.
1 to 5 years : 1 to 2 mg three times daily.
6 to 12 years : 2 to 4 mg three to four times daily.

All doses are to be taken after meals.

Symptoms and Treatment for overdosage:
Symptoms are as in 'Side effects/Adverse reactions'.
If the drug has been taken recently, the stomach should be emptied by aspiration and lavage. The patient should be kept quiet to minimise the excitation which occurs particularly in children. Convulsions and marked central nervous system stimulation should preferably be treated with diazepam or phenobarbitone intramuscularly, paraldehyde, thiopentone sodium and chlorpromazine. Severe hypotension may require fluid replacement and assisted respiration may be necessary.

Pack size: A bottle of 1000 tablets.
Blister pack: A box of 100 x 10 tablets per strip.

Storage conditions: Store at temperature 25C. Protect from light.

 

Shelf-life: 5 years.

Description: Round, yellow, convex, plain tablet with "SW" debossed on one side only.

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