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Aminophylline DBL
Contents:
Aminophylline.
Indications:
Asthma, bronchopneumonia,
bronchitis, Cheyne-Stokes respiratory, paroxysmal dyspnoea associated with
left heart failure.
Dosage:
Adult
Loading dose: 6 mg/kg.
Maintenance: 0.5 mg/kg/hr IV infusion.
Cardiac failure 0.3 mg/kg/hr.
Liver disease 0.2 mg/mg/hr.
Both cardiac failure & liver
disease 0.1 mg/kg/hr.
Children
5 mg/kg/6hourly slow IV
injection.
Contraindications:
Allergy to theophyllines,
caffeine, theobromine, hypersensitivity to ethylenediamine. Peptic ulcer,
active gastritis; severe renal or liver impairment.
Special Precautions:
Hyperthyroidism; glaucoma,
diabetes mellitus, angina pectoris. Pulmonary, CV, renal or hepatic
diseases. Pregnancy; children & elderly.
Adverse Reactions:
Gastrointestinal upset,
nervousness, urinary frequency.
Drug interactions:
Mutual antagonism with β-adrenergic
blockers. May increase CNS stimulation caused by sympathomimetics & decrease
effectiveness of lithium & phenytoin. May enhance toxicity of digitalis
glycosides..
Presentation/Packing:
Ampoules 25 mg/mL x 10 mL
x 50's |
