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Amitrid
Contents
Per tab Amiloride HCI 5 mg,
hydrochlorothiazide 50 mg.
Per mite tab Amiloride HCI 2.5
mg, hydrochlorothiazide 25mg.
Indications
Hypertension, cardiac edema,
hepatic cirrhosis with ascites & edema.
Dosage
Hypertension
1-2 tab daily.
Cardiac edema
Initially 1 tab daily, max : 4
tab daily
Contraindications
Hyperkalemia, anuria, acute renal
failure, severe progressive renal disease; diabetic nephropathy.
Special Precautions
Impaired renal or hepatic
function; pregnancy, lactation, elderly, Debilitated Systemic Lupus Erythematosus; diabetes mellitus. Monitor fluid & electrolytes.
Adverse Reactions
Metabolic disturbances;
electrolyte imbalance; anorexia; gastrointestinal effects; paresthesia,
thirst, dizziness, postural hypotension; skin rash, pruritus; weakness,
muscle cramps; minor psychiatric or visual changes; increased blood urea
nitrogen concentration.
Rarely
Cholestatic jaundice,
pancreatitis, blood dyscrasias.
Drug interactions
May enhance toxicity of digitalis
glycosides, neuromuscular action of competitive muscle relaxants, effects of
antihypertensives. Increased risk of postural hypotension with alcohol,
barbiturates, opioids. Pot-depleting effect enhanced by corticosteroids,
adrenocortical trophic hormone, carbenoxolone. Effect antagonised by NSAID.
Presentation/Packing
Tab 100's.
Mite tab 100's. |
