Blackmores Joint Formula
Indication
Adjunct to the treatment of osteoarthritis.
Properties and effects
Research shows that glucosamine may help reduce joint inflammation and
swelling, increase joint mobility, and provide temporary relief of the pain
of osteoarthritis.
Mode of action and pharmacokinetics
Glucosamine is formed in the body from glucose and the amino acid glutamine.
it is a key part of the structure of cartilage, which is essential for
proper joint function.
As we get older, cartilage becomes more susceptible to breakdown and damage,
which may result in the typical symptoms of osteoarthritis. Glucosamine
capsules can be an important additional source of this component of
cartilage as we age. Glucosamine capsules provide relief from symptoms
associated with degenerative joint conditions such as osteoarthritis.
Chondroitin sulfate is also found in cartilage, and helps joints resist
compressive loads and cope with weight-bearing activities such as running
and walking.
Blackmore Joint Formula combines glucosamine and chondroitin to help
stimulate the production and regeneration of cartilage and help relieve the
symptoms of osteoarthritis. Blackmores Joint Formula is recommended for
those with osteoarthritis and joint pain.
In the event of severe pain, it is advisable to take an anti-inflammatory
drug during the first days of treatment.
Glucosamine taken orally is 90% absorbed in the small intestine. The
glucosamine concentrationin the body peaks between 6 and 24 hours after
consuming. Glucosamine diffuses into several tissues, in particular bone and
articular cartilage. It is mainly excreted in the urine. Chondroitin sulfate
is rapidly absorbed in the gastrointestinal tract. Peak plasma levels occur
1 hour after oral administration. Chondroitin diffuses into several tissues,
including the synovial tissue and cartilage and is mainly excreted in the
urine and faeces.
Dosage
Adults - Take 1 capsule twice a day with meals, or as professionally
prescribed.
Children under 12 years - As professionally prescribed.
Contraindications, side effects, precautions and warnings
Contraindicated in people who are hypersensitive to glucosamine.
This product contains glucosamine hydrochloride, a seafood derived material.
Not recommended for people with seafood allergies.
Side effects are uncommon while using glucosamine hydrochloride. Infrequent
side effects include:
• Cardiovascular: Peripheral oedema and tachycardia were reported in
a few patients following larger clinical trials investigating oral
administration in osteoarthritis. A causal relationship has not been
established
• Central nervous system: Drowsiness, headache and insomnia have been
observed rarely during therapy (les than 1%).
• Gastrointestinal: Nausea, vomiting, heartburn, dyspepsia or
epigastric pain, constipation, diarrhoea and anorexia have been described
rarely during oral therapy with glucosamine
• Skin: Skin reactions such as erythema and pruritus have been
reported with therapeutic administration of glucosamine
• Pregnancy and breast-feeding: No evidence of risk exists in the
medical literature. However, Blackmores policy is to limit unnecessary
medications from any source during pregnancy and breast-feeding
• Interactions: None clinically significant noted in the literature
at the recommended dosage.
• Signs and symptoms of overdose: None noted in the literature.
Keep out of reach of children. Store below 30°C in a dry place away from
direct sunlight. Gelatin in hard shell is from bovine source.
Do not use the product beyond the expiry date printed on the pack.
Active ingredients per capsule
Chondroitin sulfate bovine sodium 225 mg
Glucosamine hydrochloride 750 mg
Description
White powder in a clear hard shell capsule.
Pack sizes
60 capsules
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