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Candacort Cream
DESCRIPTION
White cream containing 1.0% w/w
Clotrimazole and 1.0% w/w Hydrocortisone in an inert water-miscible base
comprising of emulsifying wax, white soft paraffin, liquid paraffin and
purified water with 0.1% Chlorocresol as preservative.
PHARMACOLOGY
Clotrimazole is a broad-spectrum
imidazole with potent anti-fungal against dermatophytes, including
Epidermophytes, Microsporum, Trichophyton spp. and Malassezia furfur, and
Candida species. It permeates the chitin of the fungal cell wall and
increases the membrane permeability to various intracellular substances.
Hydrocortisone is a topically active corticosteroid which has
potent-anti-inflammatory, anti-pruritic, and vasoconstrictive actions.
INDICATIONS
Topical treatment of tines pedis,
tinea cruris, tinea corporis due to Trichophytes canis, tinea versicolor due
to Malassezia furfur, and for cutaneous or external genital candidiasis due
to Candida albicans, when these dermal infections are accompanied by
pronounced inflammatory symptoms. Thus Candacort is particularly indicated
for the initial stages of treatment.
Once the inflammatory symptoms
have disappeared, treatment maybe continued with Candazole Cream, if
preferred.
CONTRAINDICATIONS
Hypersensitivity to Clotrimazole,
Hydrocortisone or any component in the base. The use of corticosteroid is
contraindicated in most viral infections of the skin and also tuberculosis
and acne rosacea.
DRUG INTERACTIONS
Not known.
ADVERSE EFFECTS
Infrequent local adverse effects
of Clotrimazole and Hydrocortisone include stinging, burning, oedema,
vesication. desquamation, pruritus, and urticaria.
PRECAUTIONS/WARNINGS
If irritation or sensitivity
occurs, treatment should be discontinued. Do not use on children under 2
years of age except under the advice and supervision of a doctor. Avoid
contact with eyes and mucous membranes (for external use only). Advise to
consult doctor if no improvement is seen in 4 weeks (for athlete's foot) or
2 weeks (for jock itch).
INSTRUCTIONS FOR THE PATIENT
ON THE USE OF THE CREAM
Wash and dry affected area. Apply
sparingly to the affected parts and surrounding areas and rub in twice
daily, morning and evening or as directed by your doctor or pharmacist.
Regular application is essential for successful treatment.
Once the inflammatory symptoms
have disappeared treatment may be continued with Candazole Cream, it
preferred.
Treatment should be continued for
two weeks after all clinical signs have disappeared.
Attention to hygiene is important
in the management of candidiasis, particularly of the folds and the feet.
If symptoms persist please consult your prescriber.
This preparation is for the treatment of your current condition only.
Do not allow use by any other person and dispose off unused material when
your treatment is complete.
PACKING
15g aluminium tubes or 450g in
polypropylene jars.
STORAGE
Keep container well closed.
Protect from strong light.
Store below 30°C.
For external use only.
Keep out of reach of children.
Recommended shelf-life: 3 years.
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