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Candacort Cream

DESCRIPTION

White cream containing 1.0% w/w Clotrimazole and 1.0% w/w Hydrocortisone in an inert water-miscible base comprising of emulsifying wax, white soft paraffin, liquid paraffin and purified water with 0.1% Chlorocresol as preservative.


PHARMACOLOGY

Clotrimazole is a broad-spectrum imidazole with potent anti-fungal against dermatophytes, including Epidermophytes, Microsporum, Trichophyton spp. and Malassezia furfur, and Candida species. It permeates the chitin of the fungal cell wall and increases the membrane permeability to various intracellular substances. Hydrocortisone is a topically active corticosteroid which has potent-anti-inflammatory, anti-pruritic, and vasoconstrictive actions.

 

INDICATIONS

Topical treatment of tines pedis, tinea cruris, tinea corporis due to Trichophytes canis, tinea versicolor due to Malassezia furfur, and for cutaneous or external genital candidiasis due to Candida albicans, when these dermal infections are accompanied by pronounced inflammatory symptoms. Thus Candacort is particularly indicated for the initial stages of treatment.

 

Once the inflammatory symptoms have disappeared, treatment maybe continued with Candazole Cream, if preferred.


CONTRAINDICATIONS

Hypersensitivity to Clotrimazole, Hydrocortisone or any component in the base. The use of corticosteroid is contraindicated in most viral infections of the skin and also tuberculosis and acne rosacea.

 

DRUG INTERACTIONS

Not known.


ADVERSE EFFECTS

Infrequent local adverse effects of Clotrimazole and Hydrocortisone include stinging, burning, oedema, vesication. desquamation, pruritus, and urticaria.

 

PRECAUTIONS/WARNINGS

If irritation or sensitivity occurs, treatment should be discontinued. Do not use on children under 2 years of age except under the advice and supervision of a doctor. Avoid contact with eyes and mucous membranes (for external use only). Advise to consult doctor if no improvement is seen in 4 weeks (for athlete's foot) or 2 weeks (for jock itch).

 

INSTRUCTIONS FOR THE PATIENT ON THE USE OF THE CREAM

Wash and dry affected area. Apply sparingly to the affected parts and surrounding areas and rub in twice daily, morning and evening or as directed by your doctor or pharmacist. Regular application is essential for successful treatment.

 

Once the inflammatory symptoms have disappeared treatment may be continued with Candazole Cream, it preferred.

 

Treatment should be continued for two weeks after all clinical signs have disappeared.

 

Attention to hygiene is important in the management of candidiasis, particularly of the folds and the feet.


If symptoms persist please consult your prescriber.


This preparation is for the treatment of your current condition only.


Do not allow use by any other person and dispose off unused material when your treatment is complete.

 

PACKING

15g aluminium tubes or 450g in polypropylene jars.


STORAGE

Keep container well closed.

Protect from strong light.

Store below 30C.

For external use only.

Keep out of reach of children.
Recommended shelf-life: 3 years.

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