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Carilase

 

Description

Oblong, blue uncoated tablet, bevel-edged, flat faces, "HD" and break-bar embossed on the same face.

 

Composition

Papain equivalent to 26,000 USP Units per tablet.

 

Actions and Pharmacology

Papain consists chiefly of a mixture of papain and chymopapain, proteolytic enzymes which hydrolyse polypeptides, amides and esters. It has a wider range of activity and is more difficult to destroy than either trypsin or pepsin.

 

Indications

Oral use is indicated for prevention of adhesions in sloughing and infected wounds; and for treatment of oedema and inflammatory conditions.

 

Contraindications

- Not recommended for patients with generalised or systemic infections or with disorders of blood coagulation.

- Avoid concurrent use with anticoagulants.

 

Precautions

Safety for use in pregnancy and lactation has not been established.

 

Main Side/Adverse Effects

Urticaria, pruritus, dizziness, nausea, vomiting, diarrhoea and sensitisation may occur.

 

Dosage and Administration

Adults : Oral, 2 tablets sucked or chewed 4 times daily for the 1st day, followed by 1 tablet 4 times daily for about 5 days.

Children : As directed by physician.

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