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Cinna

Cinnarizine is a new type of vasodilator in the treatment of consequences of cerebral and coronary arteriosclerosis. It also has the properties and uses of the antihistamines, such as Meclizine, but it is mainly used for the symptomatic treatment of nausea and vertigo due to Meniere's disease and other labyrinthine disturbances.

Ingredient(s)
Each tablet contains: Cinnarizine 25mg

Action(s)
1. Cinnarizine increases and normalizes cerebral circulation and thereby increase the oxygen supply of the arteriosclerotic cerebral vessels. It prevents and eliminates vascular spasms of the labyrinth.

2. The improvement of cerebral circulation is also sustained by the fact that Cinnarizine increases the blood flow as well as the blood and oxygen supply to the heart muscle. The heart capacity is improved.

3. The mechanism of action of Cinnarizine may be explained by its direct inhibitory action on the tonus of the smooth muscles of certain arterioles which renders less sensitive to certain contractile substances such as angiotensin.

Indication(s)
For the symptomatic treatment of nausea and vertigo due to Meniere's disease and other labyrinthine disturbances; for the prevention of motion sickness; also used in the management of peripheral arterial disease.

Dosage and Administration
The usual dose is 15 - 30mg three times daily.
Children aged 5 to 12 years may be given half the adult dose.
For motion sickness: 30mg may be taken 2 hours before the start of the journey and 15mg every 8 hours during the journey.

Precaution(s) / Warning(s)
1. May cause drowsiness, patients affected in this way should not drive or operate machinery.
2. Avoid alcohol drink.
3. It should be used with reasonable caution in hypotensive patients (It has been found to decrease blood pressure significantly).
4. It is not advisable to administer in pregnant women.

Side Effect(s) / Adverse Reaction(s)
Only high doses may occasionally cause a slight sleepiness which disappears rapidly after reducing the dose. Other side effects are skin allergic reaction and fatigue.

Shelf-Life
3 years from the date of manufacture.

Storage Condition(s)
Keep in a tight container. Store at temperature below 30C. Protect from light and moisture.

Packing(s)
Plastic bottle of 100's, 200's, 250's, 500's, 1000's and 2000's (for export only).
Blister packing of 10's x 10 and 10's x 100.

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