Dyna Ferrous Fumarate
Colour : Brown
Shape : Round, Biconvex and Scored
Coating : Film-coated
EACH TABLET CONTAINS
Ferrous Fumarate ............................. 200 mg
Ira essential component in the physiological formation of hemoglobin,
adequate amounts of which are necessary for effective erythropoies s and the
resultant oxygen transport capacity of the blood. A similar function is
provided by Iron n myoglobin production. Iron also serves as a cofactor of
several essential enzymes, including cytochromes that are involved in
electron transport. Iron is necessary for catecholamine metabolism and the
proper functioning of neurotrophils. When taken orally, in food or as a
supplement, Iron passes through the mucosal cells in the ferrous state and
is bound with the protein transferrin. In this form, Iron is transported in
the body to bone marrow for red blood cell production.
Iron in irregularly and incompletely absorbed from the gastrointestinal
tract, the main site absorption being the duodenum and jejenum absorption is
usually increased in conditions of Iron deficiency or when given in the
fasting sate. Absorption of Iron may be reduced in certain disease states.
Protein binding is very high (about 90% or more).
For the treatment or prophylaxis of Iron deficiency anaemia.
2 to 3 tablets daily, in divided doses, or as directed by the physician.
Except under special circumstances, this medication should not be used when
the following medical problems exist: hemachromatosis or hemosiderosis.
Risk-benefit should be considered when the following medical problems exist:
Alcoholism, allergies, asthma, hepatic function impairment, kidney disease,
intestinal tract inflammatory conditions, peptic ulcer, rheumatoid arthritis
or sensitivity to Iron.
WARNING AND PRECAUTIONS
Iron salts should not be given to patients receiving repeated blood
transfusions or to patients with anaemias not produced by Iron deficiency
unless Iron deficiency is also present. Oral Iron therapy should not be
administered concomitantly with parenteral Iron. Care should be taken when
given to patients with Iron storage or Iron absorption diseases,
haemoglobinopathies, or existing gastrointestinal disease. The absorption of
Iron salts and tetracyclines is diminished when they are taken concomitantly
by mouth. If treatment with both drugs is required, the Iron salt should be
administered 2 hours before or 3 hours after the tetracycline. The
absorption of iron salts may also be decreased by some antacids. Iron salts
reduce the effects of penicillamine. The response to Iron may be delayed in
patients receiving concomitant chloramphenicol therapy.
Combination containing any of the following medications (depending on the a
mount present) may interact with this medication: acetohydroxamic acid,
alcohol, tetracyclines, etidronate, penicillamine or trientine, pancreatin
or pancrelipase, dimercaprol, chelating agents, antacids and calcium or zinc
SIDE EFFECTS/ADVERSE REACTIONS
The oral administration of Iron preparations sometimes produces
gastrointestinal irritation and abdominal pain with nausea, vomiting,
diarrhoea or constipation.
SYMPTOMS AND TREATMENT OF OVERDOSE
Iran overdose may have corrosive effects on the gastrointestinal mucosa;
necrosis and perforation may occur; stricture formation may subsequently
follow. Symptoms may include epigastric pain, diarrhoea, n vomiting and
haematemesis. Circulatory failure may follow if the diarrhoea and
haemorrhage are severe. Hours or days later, after apparent recovery,
metabolic acidosis, convulsions, and coma may occur. If the patient
survives, symptoms of acute liver necrosis may develop and may lead to death
due to hepatic coma. In treating Iron poisoning, speed is essential to block
absorption of Iron from the alimentary tract. Wash out the stomach with a 1%
solution of sodium bicarbonate as quick as possible and then to give 5 to 10
g of desferrioxamine mesylate in 50 to 100 ml of water to chalet, any Iran
left in the stomach and prevent further absorption. To eliminate Iron
already absorbed, 1 to 2 g of Desferrioxamine Mesylate may be given
intramuscularly o intravenously by slow infusion. If desferrioxamine is not
available, empty the stomach immediately by emesis and lavage using a 1 to
5% solution of Sodium Bicarbonate, and Leave up to about 300 ml of the
solution in the stomach; Sodium Bicarbonate forms poorly absorbed Ferrous
Carbonate with any ferrous ions. Other measures include correction of lost
Children under 4 years of age
Adults and children 4
years of age
Pregnant & Lactating
Plastic container of 1000's (For EXPORT/TENDER Only).
Blister pack of 100 x
3 years from the date of manufacture.
KEEP OUT OF REACH OF CHILDREN
Keep Container Tightly Closed
Store In A Dry
Place Below 25°C
Protect From Light