Contents:

Metoclopramide hydrochloride

Indications:

Gastric disorder & dysfunction of bowels, post-operative states & inclination to retention in connection with pylorus & duodenum ulcer. Nausea & vomiting. Prior to X-ray & gastro-enterological exam to accelerate gastric discharge & small bowel transit time.

Dosage:

Adult

Nausea & vomiting, dyspepsia 1-2 tab three times daily.

Disorders of motility 1-2 tab daily.

Premedication 2 tab about 10 min before gastroenterological exam.

Contraindications:

Whenever stimulation of GI motility might be dangerous, eg intestinal obstruction; pheochromocytoma, epilepsy.

Special precautions:

Children & young patients; pregnancy, lactation; diabetes, depression; patients taking other drugs that can also cause extrapyramidal reactions..

Adverse reactions:

Extrapyramidal reactions, dizziness, fatigue, drowsiness, headache, depression, restlessness, GI disturbances, hypertension.

Drug interactions:

Effects antagonised by anticholinergics & narcotic analgesics. Increased sedation with CNS depressants. Absorption of drugs ( digoxin, cimetidine) may be impaired  absorption from small intestine increased ( paracetamol, tetracyclines, levodopa). Insulin require may be altered due to change in timing of food delivery to intestines.

Presentation/Packing :

Tab 10 mg x 1000's