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Fenadium

 

Contents:

Diclofenac sodium

 

Indications:

Inflammatory & degenerative forms of rheumatism. Acute musculoskeletal disorders, acute gout, post-traumatic & post-operative inflammation & swelling. Pain, renal & biliary colic.

 

Dosage:

Adult 75-150 mg/day. Children 0.5-3 mg/kg body weight/day.

Dysmenorrhoea Up to 200 mg/day.

 

Contraindications:

Peptic ulcer. Hypersensitivity to aspirin, other prostaglandin synthetase inhibiting drugs.

 

Special Precautions:

Gastrointestinal  disease (GI), Crohn's disease; impaired hepatic, cardiac or renal function. Porphyria; extracellular volume depletion; asthma, elderly. Patients on diuretics, anticoagulant or anti-diabetics. Period monitoring of liver function  blood counts.

 

Adverse Reactions:

Occasionally GI disorders, edema, headache, dizziness, vertigo, rash, elevation of serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT)

 

Rarely Peptic ulcer, GI bleeding; hepatitis.

Isolated cases : Disturbances of sensation, erythema multiforme, purpura; abnormalities of renal function; blood dyscrasias.

 

Drug interactions:

Increases plasma concentration of lithium, methotrexate, warfarin. May alter plasma concentration sulfonylureas. May reduce effects of diuretics, β-blockers, digoxin, captopril, triamterene.

 

Presentation/Packing:

Tab

25 mg (Film-coated) x 1000's,

50 mg (Enteric-coated) x 1000's.

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