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Hemosol
Suppositories
Description : Grey
coloured suppositories
Contents
Each suppository contains zinc
oxide 300mg, benzyl benzoate 33mg and balsam peru 50mg
Indications
For the relief of symptoms for
uncomplicated hemorrhoids ( eg pain, itch, soreness ), minor rectal
inflammation and irritation. It may also be used in pre- and post-hemorrhoidectomy,
anal fistula, thrombosed/sclerosed anorectal veins, and as a lubricant for
easy bowel movement.
Pharmacology
Zinc oxide is applied externally
as a mild astringent for the skin and a soothing protective for slight
excoriations. Benzyl benzoate is acomponent of cinnamon oil and balsam peru.
Balsam peru is a resin that is extracted from a tropical tree called
myroxilon, which when converted into oil, becomes a strong healing substance
for any kinds of skin irritation. It has mild antiseptic action by virtue of
its content of cinnamonic and benzoic acids. It is used for symptomatic
relief of hemorrhoids, eg. ulcers and puritis.
Rarely absorbed as it is used
externally. If topical benzyl benzoate is systemically absorbed, it is
rapidly hydrolyzed to benzoic acid and benzyl alcohol which is further
oxidized to benzoic acid. The benzoic acid is conjugated with glycine to
form hippuric acid and which is primarily excreted in the urine.
Contraindications
It is contraindicated in patients
known hypersensitive to any of its ingredients and serious rectal pathology.
Side effects/Adverse reactions
It is irritant to the eyes and
mucous membranes. It causes slight irritation to the skin eg. burning
sensation and itch. Skin sensitization has also occurred.
Precautions
Use should be discontinued if
redness, irritation, swelling and pain persists or increases. Risk benefits
should be considered for pregnant or lactating mothers.
Pregnancy & Lactation
Risk benefits should be
considered when use in pregnant and lactating mothers, although safety of
use has not been established.
Dosage and administration
One suppository to be inserted
well into the rectum twice daily ( morning and evening ) and after each
bowel movement.
Treatment of overdosage
Unlikely to have overdosage. If
stinging or burning sensation occurs, treatment is symptomatic. Allergic
contact dermatitis may be relieved with topical corticosteroids or
emollients. Affected area may also be washed with water copiously. If
further irritation occurs, consult the doctor.
Storage conditions
Keep container tightly closed.
Stored in a dry place below 30°C. Protect from light.
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