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Hemosol Suppositories

Description : Grey coloured suppositories

 

Contents

Each suppository contains zinc oxide 300mg, benzyl benzoate 33mg and balsam peru 50mg

 

Indications

For the relief of symptoms for uncomplicated hemorrhoids ( eg pain, itch, soreness ), minor rectal inflammation and irritation. It may also be used in pre- and post-hemorrhoidectomy, anal fistula, thrombosed/sclerosed anorectal veins, and as a lubricant for easy bowel movement.

 

Pharmacology

Zinc oxide is applied externally as a mild astringent for the skin and a soothing protective for slight excoriations. Benzyl benzoate is a component of cinnamon oil and balsam peru. Balsam peru is a resin that is extracted from a tropical tree called myroxilon, which when converted into oil, becomes a strong healing substance for any kinds of skin irritation. It has mild antiseptic action by virtue of its content of cinnamonic and benzoic acids. It is used for symptomatic relief of hemorrhoids, eg. ulcers and puritis.

 

Rarely absorbed as it is used externally. If topical benzyl benzoate is systemically absorbed, it is rapidly hydrolyzed to benzoic acid and benzyl alcohol which is further oxidized to benzoic acid. The benzoic acid is conjugated with glycine to form hippuric acid and which is primarily excreted in the urine.

 

Contraindications

It is contraindicated in patients known hypersensitive to any of its ingredients and serious rectal pathology.

 

Side effects/Adverse reactions

It is irritant to the eyes and mucous membranes. It causes slight irritation to the skin eg. burning sensation and itch. Skin sensitization has also occurred.

 

Precautions

Use should be discontinued if redness, irritation, swelling and pain persists or increases. Risk benefits should be considered for pregnant or lactating mothers.

 

Pregnancy & Lactation

Risk benefits should be considered when use in pregnant and lactating mothers, although safety of use has not been established.

 

Dosage and administration

One suppository to be inserted well into the rectum twice daily ( morning and evening ) and after each bowel movement.

 

Treatment of overdosage

Unlikely to have overdosage. If stinging or burning sensation occurs, treatment is symptomatic. Allergic contact dermatitis may be relieved with topical corticosteroids or emollients. Affected area may also be washed with water copiously. If further irritation occurs, consult the doctor.

 

Storage conditions

Keep container tightly closed. Stored in a dry place below 30C. Protect from light.

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