HEPARIN

Contents:

Heparin sodium

Indications:

Prophylaxis & treatment of venous thrombosis & pulmonary embolism. Treatment of myocardial infarction & arterial embolism. For prevention of clotting in arterial & heart surgery & prevention of cerebral thrombosis. As an anticoagulant in blood transfusions, extracorporal circulation, dialysis & for lab purposes.

Dosage:

Hemodialysis: 7500-12,000 iu; IV admin 5000-10,000 iu 4 hourly. SC admin 10,000 iu 8 hourly.

Low-dose heparin prophylaxis: 5000 iu SC 2-6 hourly pre-operative & 8-12 hourly post-operative for 10-14 days or until the patient is mobile.

Contraindications:

Hemorrhagic diseases, thrombocytopenia, hemophilia; subacute bacterial endocarditis; peptic ulcer; severe hypertension; patient who has recently undergone surgery at site where hemorrhage is a special risk; advanced renal or hepatic disease, jaundice.

Special Precautions:

Pregnancy, elderly. Increased resistance is frequently encountered in thrombosis, thrombophlebitis infected with thrombotic tendencies, cancer, post-surgical patients.

Adverse Reactions:

Transient alopecia, diarrhea; osteoporosis with spontaneous fractures. Occasionally, febrile or allergic reactions.

Drug Interactions:

Drugs that interfere with platelet-aggregation reactions may induce bleeding. Digitalis, tetracycline, nicotine or antihistamine may partially counteract the anticoagulant action.

Presentation/Packing:

Vial 5000 iu x 5 mL x 5's.