150 mg/300 mg tab Duodenal
ulcer & benign gastric ulcer; prevention of NSAID associated duodenal
ulcers. Treatment of post-op ulcer, Zollinger-Ellison syndrone & oesophageal
reflux disease, & conditions where reduction of gastric secretion & acid
output is desirable.
EVT tab Duodenal & gastric ulcer, Zollinger-Ellison syndrome, treatment adjunct in RA for relief of GI
symptoms associated with NSAIDs, reflux oesophagitis, stress ulcers,
short-bowel (anastomosis) syndrome, prophylaxis of GI haemorrhage from
stress ulceration in seriously ill patients, prophylaxis of recurrent
haemorrhage in patients with bleeding peptic ulcers & before GA in patients
at risk of acid aspiration (Mendelson's syndrome), especially obstetric
patients during labour, hypersecretory states associated with systemic
mastocytosis or basophilic leukemia with hyperhistaminemia.
150 mg/300 mg tab Adult
150 mg bd.
Duodenal ulcer, gastric ulcer,
oesophageal reflux Single bedtime dose of 300 mg. Maintenance:
150 mg at bedtime or for oesophageal reflux disease 150 mg bd or 300 mg at
bedtime for 8-12 week.
Severe oesophagitis 150 mg
qds for up to 12 week.
150 mg tds. Max: 6 g/day.
Chronic episodic dyspepsia
150 mg bd for up to 6 week.
Patients at risk of acid
aspiration syndrome 150 mg 2 hr before induction of general anaesthetic
& also 150 mg the previous evening.
150 mg bd for at least 4 week. Maintenance: 150 mg nocte.
Prophylaxis against duodenal
ulceration 150 mg bd during therapy with NSAIDs.
GERD 150 mg bd for max 8
Initially 150 mg bd-tds. max: 6 g daily.
Prophylaxis of GI haemorrhage
from stress ulceration in seriously ill patients, prophylaxis of recurrent
haemorrhage in patients with bleeding peptic ulcers 150 mg bd.
Severe cirrhosis severe
renal impairment, hepatic impairment. Pregnancy & lactation.
Hepatitis with or without
jaundice. Acute pancreatitis. Leucopenia, thrombocytopenia, agranulocytosis,
pancytopenia. Bradycardia & AV block. Headache, dizziness, rare cases of
reversible mental confusion, depression & hallucinations. Rash, arthralgia &
Phenytoin, warfarin, theophylline,
nifedipine & alcohol. Antacids, procainamide.
Tab 150 mg x 10 x 10's. 300 mg x
5 x 10's.
EVT effervescent tab (
Coolmint flavour) 150 mg x 10's.
US FDA Preg Cat, : B