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Hova Expectorant

Description
Brown, viscous liquid with raspberry flavour

Composition
Each 5 ml contains:

Diphenhydramine Hydrochloride 14.0 mg

Ammonium Chloride 135.0 mg

Sodium Citrate 57.0 mg

Actions and Pharmacology
Diphenhydramine, an antihistamine, acts by competing with histamine for H1 -receptor sites on effector cells. Its muscarinic actions provide a drying effect on the nasal mucosa. It also suppresses the cough reflex by a direct effect on the cough center in the medulla of the brain. Both ammonium chloride and sodium citrate are useful ingredients in expectorants. It is readily absorbed orally, metabolised in the liver and excreted in the urine.

Indications
For control of cough due to colds or allergy, and alleviation of nasal and bronchial congestion.

Contraindications
Avoid in patients known to be hypersensitive to antihistamines.
Not recommended in patients with hepatic or renal function impairment and in nursing mothers.
It should not be used in newborn or premature infants because of the higher risk of adverse effects with antihistamines.

Precautions
Caution in patients with glaucoma, prostatic hypertrophy, cardiovascular disease, hypertension or acute asthma.

This medication may cause drowsinesse Caution when driving or operating machinery. Avoid alcoholic beverages.

Safety for use in pregnancy has not been established.
Not to be used in children less than 2 years of age.
To be used with caution and doctor's advice in children 2 to 6 years of age.

Main Side/Adverse Effects
Drowsiness, nausea, vomiting.
Geriatric patients are especially susceptible to the anticholinergic side effects, such as dryness of mouth and urinary retention (especially in males), of the antihistamines. If these side effects occur and continue or are severe, medication should probably be discontinued.

Drug Interactions
Concurrent use with alcohol, other CNS depressants, tricyclic antidepressants, or antimuscarinics may potentiate the effects of either these medications or diphenhydramine.
Co-administration of monoamine oxidase (MAO) inhibitors may prolong and intensify the antimuscarinic effects of diphenhydramine and is generally not recommended.

Overdosage
Clinical features: Drowsiness, headache, tachycardia, disorientation, staggering gait, hallucinations, respiratory depression, convulsions. Treat overdosage by emesis or gastric lavage, if appropriate, with the necessary symptomatic and supportive measures, if required.

Dosage and Administration
Adults :

Oral, 10 ml every six hours.
Children :

2 to 6 years : Oral, 2.5 ml every six hours, as needed, not exceeding 10ml a day.

7 to 12 years : Oral, 5 ml every six hours, as needed, not exceeding 20ml a day.

 

Storage :

Store below 25C.


Presentation/Packing :

Expectorant x 3.6 Litres, 100 ml, 120 ml

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