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Medicap

Capsules


Composition
Each capsule contains Mefenamic Acid 250mg


Properties
Medicap contains an analgesic with anti-inflammatory and antipyretic action.


Indications
Medicap is indicated for the relief of muscular aches and sprains, toothache, headache, bursitis, dysmenorrhoea and mild to moderate pain in arthritis.


Dosage
Adults: Two capsules initially, followed by one capsule four times a day, with or after food.


Contraindications
Do not use in patients with ulceration or inflammation of the gastrointestinal tract, impaired renal or hepatic function, in hypersensitive patients and in pregnancy.


Precautions
Discontinue treatment if diarrhoea or rashes occur.

Use with caution in epilepsy and in asthmatic patients.

WARNING
NSAID: Risk of GI ulceration, bleeding and perforation
Serious GI toxicity such as bleeding, ulceration and perforation can occur at any time with or without warning symptoms, in patients treated with NSAID therapy. Although minor upper GI problems (e.g. dyspepsia) are common, usually developing early in therapy, prescribers should remain alert for ulceration and bleeding in patients treated with NSAIDs even in the absence of previous GI tract symptoms.
Studies to date have not identified any subset of patients not at risk of developing peptic ulceration and bleeding. Patients with prior history of serious adverse events and other risk factors associated with peptic ulcer disease (e.g. alcoholism, smoking, corticosteroid therapy) are at increased risk. Elderly or debilitated patients seems to tolerate ulceration or bleeding less than other individuals and account for most spontaneous reports for fatal GI events.


Drug Interactions
The effects of lithium therapy may be potentiated by mefenamic acid.


Side Effects
These may include gastrointestinal disturbances, bleeding, occasionally peptic ulceration, hypersensitivity reactions; skin rashes, drowsiness, dizziness, headaches and haematological effects such as haemolytic anaemia and thrombocytopaenia.


Overdosage
In cases of overdosage and poisoning, hospital admission is strongly advised. Symptoms include severe form of side-effects and convulsions. Aspiration and gastric lavage may be necessary. Activated charcoal may be useful in reducing absorption of mefenamic acid in acute cases. Symptomatic and supportive treatment may be given.


Shelf-life
5 years from the date of manufacture.


Presentation
Blue / light blue hard gelatin capsules printed with "XSP" in dispensing pack of 1000's.


Storage
Store below 30C.

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