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ORAL
AID LOTION
Description
A milky white, flavoured,
homogeneous, colloidal solution. It contains Lignocaine 2.5%, Chlorhexidine
hydrochloride BP 0.5% and Triamcinolone Acetonide BP 0.1%.
Preservatives : Methylparaben
0.21%, Propylparaben 0.031%.
Indications
Oral Aid Lotion is an anaesthetic,
antibacterial, and antiinflammatory agent, which is used in mouth infections
or oral lesions. It heals and relieves pain and discomfort in acute and
chronic lesions of the gum, palate, cheek and tongue.
Mechanisms of action
Lignocaine
Local anaesthetics block both the
initiation and conduction of nerve impulses by decreasing the neuronal
membrane's permeability to sodium ions. This reversibly stabilises the
membrane and inhibits depolarisation, resulting in conduction blockade.
Chlorhexidine
HCI
Because of its positive charge,
cholorhexidine is absorbed onto the surfaces of teeth, plaque, and oral
mucosa, which is gradually released from these sites for up to 24 hours,
providing a continuing bacteriostatic effect.
Triamcinolone
Acetonide
Corticosteroids diffuse across
cell membranes and complex with specific cytoplasmic receptors, resulting in
anti-inflammatory effects of Oral Aid Lotion.
Dosage
Apply to the affected area, up to
every one to two hours as required.
Side effects
Side effects of Oral Aid Lotion
include allergic contact dermatitis ( skin rash, redness, itching, or hives
), angioedema ( large, hive-like swellings on skin or in mouth or throat),
burning, stinging, swelling, or tenderness not present before therapy.
Transient taste disturbances and a burning sensation of the tongue may occur
on initial use.
Contraindications
Oral Aid Lotion is
contraindicated in patients who are sensitive to lignocaine, chlorhexidine
and triamcinolone acetonide.
Precautions
Oral Aid Lotion should be used
with caution when there is local infection at area of treatment. Caution is
also needed when there is severe traumatized mucosa as it may increase
absorption of anaesthetic, leading to increased risk of systemic toxicity.
Herpes simplex at treatment site may be transmitted to other sites,
including the eye and Oral Aid Lotion should be used with caution. Again,
caution is needed in patients with anterior tooth restorations ( front-tooth
fillings ) and periodontitis.
Drug Interactions
At recommended doses, drug
interactions are uncommon. However, in rare cases where Oral Aid Lotion is
used in large quantities, used repeatedly or swallowed, lignocaine is
systemically absorbed and interactions with beta-adrenergic blocking agents,
cimetidine, and other amide local anaesthetic-derivative antiarrythmic
agents have been reported. Long term administration of enzyme-inducing
agents such as phenytoin may increase dosage requirements of lignocaine.
Overdosage
When used as recommended,
overdosing with Oral Aid Lotion is rare.
Presentation
6 ml
Storage conditions and user
instructions
Keep container tightly
close.
Store in a dray place blow 30°C.
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