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Parmol
Descriptions
Parmol 120 Syrup
Orange, viscous liquid with strawberry flavour.
Parmol 250 Suspension
Pink, viscous suspension with rasberry flavour.
Orange, viscous
suspension with orange flavour.
Compositions
Parmol 120 Syrup : Paracetamol 120 mg/5 ml.
Parmol 250 Suspension :
Paracetamol 250 mg/5 ml.
Actions and Pharmacology
Paracetamol is an analgesic-antipyretic. These effects may be due to
inhibition of prostaglandin synthesis in the CNS and through a peripheral
action by blocking pain-impulse generation. It is rapidly absorbed orally,
metabolised in the liver, and excreted in the urine.
Indications
For relief of minor types of pain such as headache, myalgias, toothache and
febrile conditions.
Contraindications
It is contraindicated in patients with known hypersensitivity to paracetamol.
Precautions
Caution in patients with hepatic or renal function impairment.
Check with physician if symptoms do not improve or if fever lasts longer
than 3 days or recurs.
Chronic use should be avoided,
unless otherwise directed by physician.
Side/Adverse Effects
In recommended therapeutic dosage, paracetamol is usually well tolerated.
Rarely, hypersensitivity and haematological reactions may occur.
Drug Interactions
Risk of hepatotoxicity with single toxic dose or prolonged use of
paracetamol may be increased in chronic alcoholics or in patients regularly
taking other hepatic enzyme-inducing agents.
Overdose
Clinical features : Nausea, vomiting, epigastric discomfort,
hypoprothrombinaemia, hepatic or renal failure and metabolic acidosis or
coma in very severe cases.
Treat overdosage by emesis or gastric lavage, if indicated. Administer N-acetylcysteine
orally (start within 10 hours after ingestion), 140 mg of 20% solution per
kg as a loading dose, followed by 70 mg/kg every 4 hours for 3 days with the
necessary supportive treatment if required.
Dosage and Administration
Parmol 120 Syrup
Children
1 to 6 years : 1 to 2 teaspoonful
(5-10 ml) 3 to 4 times daily.
7 to 12 years : 2 to 4
teaspoonful (10-20 ml) 3 to 4 times daily.
Parmol 250 Suspension
Adult
2 to 4 teaspoonful (10 to 20 ml)
not exceeding 80 ml daily.
Children
1 to 6 years half to 1
teaspoonful (2.5 to 5 ml) 3 to 4 times daily.
7 to 12 years : 1 to 2
teaspoonful (5 to 10 ml) 3 to 4 times daily.
Note: The information given here is limited, for further information consult
your doctor or pharmacist.
Storage
Store below 25°C. Protect from
light and freezing.
Presentation/Packing
Syrup 120 mg/5 ml x 3.6 Litres,
100 ml, 60 ml;
Suspension 250 mg/5 ml x 3.6
Litres, 100 ml, 60 ml.
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