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 Red Chicken Brand
Fever mixture
Description and Active Ingredient
Red Chickens Brand Fever Mixture
is a clear, light-golden coloured liquid containing paracetamol in quantity
of 120 mg in 5 ml.
Pharmacological Information
The active ingredient,
paracetamol, reduces minor pain and fever. Pain is caused by the body
producing a chemical substance called Postaglandins. As paracetamol can stop
the body from producing this substance, pain is reduced. Paracetamol is also
able to act on the heat regulatory organ located in the brain to produce
more heat loss during fever, resulting in the normalization of the body
temperature.
After ingestion, paracetamol is
quickly absorbed within 10 to 60 minutes. It takes effect within this time
period. About 95% of absorbed paracetamol is converted to excreatable
by-products in the liver and passed out in the urine. Only 5% passed out in
the unchanged form.
Indication
For the relief of fever, mild to
moderate pain (Headache, teething pain) and discomfort due to common cold
and flu.
Adverse Effects
Side effects of paracetamol is
usually mild. Inflammation of the pancreas, skin rashes and allergic
reactions occur occasionally. There have been reports of charges relating to
blood cells.
Precautions and Warnings
Use paracetamol with care in
patients with impaired kidney or liver function and in patients taking other
drugs that affect the liver.
This preparation contains
Paracetamol. Do not take any other Paracetamol containing medicines at the
same time.
Drug Integrations
Paracetamol may interfere with
anti-coagulant drugs.
Recommended Dosage
Infants 3 months to 1 year : half
to one teaspoonful (2.5-5ml) three to four times a day.
Children 1 year to 6 years : one
to two teaspoonful three to four times a day.
Children 7 to 12 years : two to
four teaspoonful three to four times a day.
Adult : six teaspoonful three to
four times a day.
The above dosages may need to be
reduced in patients with liver or kidney failure.
Overdosage
After taking 150 mg/kg or more
causes drowsiness, confusion, liver tenderness, low blood pressure, cardiac
arrhythmias, nausea, vomiting, jaundice and acute renal failure. Liver
cirrhosis can occur after repeated ingestion at toxic doses.
Treatment
As an emergency measure, remove
the remaining drug in the stomach in inducing emesis with Ipecac Syrup
within one to two hours of ingestion, provided the respiration is not
depressed. For patients above 5 years old, 30 ml of Ipecac Syrup followed
immediately by two to three glasses (240-360 ml) of water is recommended.
Repeat dose 20 minutes later, if necessary.
If there is no emesis after the
administration of Ipecac syrup or if respiration is depressed, stomach
should be emptied by airway-protected gastric aspiration & lavage and a
saline purgative should be given to promote peristalsis. Avoid suing
activated charcoal, as it will interfere with the absorption of N-acetylcisteine
later.
N-acetylcisteine is given as an
antidote and must be administered within ten hours after ingestion. The oral
loading dose is 140 mg/kg and followed by maintenance dose of 70 mg/kg every
four hours for three days. if the patient vomits within one hour of
administration, the dose should be repeated.
Packing
Red Chickens Brand Fever Mixture
is available in size of 30 ml and 60 ml.
Storage and Shelf-life
Store in a cool dry place away
from direct sunlight. The recommended shelf-life is three years.
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