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Tolnaderm cream & lotion 1%Tolnaderm cream & lotion 1%

 


1. Tolnaderm Cream White opaque cream containing 1% w/w of Tolnaftate solubilised in a base containing Polyethylene glycol with Methyl paraben 0.16% and Propyl paraben 0.03% as preservatives.


2. Tolnaderm Lotion Clear viscous liquid containing 1% w/v of Tolnaftate in Polyethylene glycol.


ACTIONS:

Tolnaftate is effective in the treatment of the majority of cutaneous mycoses caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, Epidermophyton floccosum and Pityrosporum orbiculare, but is ineffective against Candida or bacteria. Infections due to Trichophyton rubrum may relapse and a second course of treatment may be required.


PHARMACOLOGY

Tolnaftate inhibits the growth of Epidermophyton, Microsporum, Trichophyton spp., and Malassezia furfur, but it is not active against Candida spp. or bacteria.

 

INDICATIONS

The topical treatment of tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (body ringworm), tines barbae (ringworm of the face and neck) and tinea manuum due to infection with Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Epidermophyton floccosum and tinea versicolor due to Pityrosporum orbiculare. Tolnaderm Cream is indicated in tinea infections of the skin especially the nonhairy areas of the body and including the groin. The vanishing cream base makes it cosmetically acceptable and there is no staining of the skin or clothing from the preparation. Tolnaderm Lotion is nonaqueous and miscible with the exudates of fungal infections of the skin; it penetrates lesions without destruction of the epidermis. Tolnaderm Lotion is odourless, greaseless and does not stain or discolour the skin, hair, nails or clothing. Tolnaftate preparations are not suitable for deep infections of the nailbed and hair follicles but maybe applied concomitantly with a systemic agent.

 

CONTRAINDICATIONS

Hypersensitivity to Tolnaftate or any component in the base.

 

DRUG INTERACTIONS

Not known.


ADVERSE EFFECTS

Skin reactions to Tolnaftate including irritation and pruritus may occur; contact dermatitis has been reported.


PRECAUTIONS/WARNINGS

If irritation or sensitivity occurs, treatment should be discontinued. Do not use on children under 2 years of age except under the advice and supervision of a doctor. Avoid contact with eyes and mucous membranes (for external use only). Advise to consult doctor if no improvement is seen in 4 weeks (for athlete's foot) or 2 weeks (for jock itch). Not for ophthalmic use.

 

RECOMMENDED DOSAGE

Wash and dry the infected area. Apply small amount of cream or lotion and spread evenly on infected area 2 or 3 times daily for 2 to 3 weeks (or 4-6 weeks if thickening of the skin has occurred, or the hyperkeratotic lesions can be treated with 10% Salicylic acid ointment alternating with Tolnaderm). When pruritus is present, it is usually relieved in 24 to 72 hours. Involution of interdigital lesions due to susceptible fungi is very often complete in 7 to 21 days. Treatment should be continued for 2 to 3 weeks after the infection has cleared to help prevent remission. Attention to hygiene is important in the management of fungal infections particularly to all the folds and creases.


PACKING

Tolnaderm Cream Plastic jar of 450g and collapsible tube of 15g.

Tolnaderm Lotion Plastic bottle of 10ml.


STORAGE

Keep container well closed. Protect from strong light. Store below 30C. For external use only. Keep out of reach of children. Recommended shelf-life: 3 years.

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