What is Xenical
Each Xenical capsule contains
120mg of the active substance orlistat.
The capsule also contains the
additional excipients microcrystalline cellulose, sodium starch glycollate,
povidone, sodium lauryl sulphate and talc. The capsule shell consists of
gelatine, indigo carmine ( E132 ) and titanium dioxide ( E171 ).
Xenical is supplied as hard
capsules in blister packs. Xenical 120mg capsules are turquoise with "ROCHE
XENICAL 120" printed in black ink.
What is Xenical use for ?
Xenical is an oral prescription
weight loss medication used to help obese people lose weight and keep this
weight off, without suppressing your appetite. Xenical works in your
intestines, where it blocks some of the fat you eat from being absorbed.
This undigested fat is then eliminated in your bowel movements. Xenical
should be taken with a low-fat, well-balanced, calorie-controlled diet and
other appropriate measure such as exercise.
How does Xenical work ?
If you eat an excess amount of
fat or calories, the excess is stored as fat by the body resulting in weight
gain. When you eat fat, your body breaks it down into its simplest
components so that it can be absorbed. Enzymes in your intestinal tract,
called lipases, help digest ( or break down ) fat. When you take Xenical
with meals, Xenical attaches to the lipases and blocks them from breaking
down some of the fat you have eaten. The undigested fat cannot be absorbed
and is eliminated in your bowel movements. By working this way, xenical
helps block about 30% of the fat eaten in food from being absorbed by your
Who should use Xenical ?
Xenical may be right for you if
you are considerably overweight ( at least 30% above ideal weight or a body
mass index of 30 or greater ). Xenical may also be right for you if you are
overweight ( at least 20% above ideal weight or a body mass index of 27 or
great ) and also have other risk factors such as high blood pressure, high
cholesterol, heart disease, or diabetes.
Who should not use Xenical ?
Those who :
* consistently have problems
absorbing food ( chronic malabsorption ); or
* have symptomatic cholelithiasis
( painful gall stones )
* are pregnant or are
breastfeeding a child; or
* have ever had an allergic
reaction to orlistat or any of the inactive ingredients in Xenical.
What should I tell my doctor
before taking Xenical ?
Before beginning treatment with
Xenical, make sure your doctor knows if you are :
* allergic to any medicines,
foods, or dyes;
* taking any other weight-loss
* taking cyclosporine;
* taking any other medicines (
including those not prescribed by your doctor );
* taking any dietary supplements,
including herbal products;
* planning to become pregnant; or
* anorexic or bulimic.
This information will help you
and your physician decide if the expected advantages of Xenical are grater
than any possible disadvantages.
Can I take Xenical while
taking other medications ?
be sure to discuss with your
doctor all medications ( including herbal products ) you are currently
taking, including medicines you can get without a prescription (
over-the-counter), to determine if Xenical can be taken in addition to these
How should I take Xenical ?
The recommended dose is one 120mg
capsule by mouth with liquid at each main meal that contains fat. Take
Xenical during meals or up to one hour after a meal.
If you occasionally miss a meal
or have a meal without fat, you can omit your dose of Xenical.
The therapeutic benefits of
Xenical ( including weight control and improvement of risk factors ) are
continued with long-term administration.
You should use Xenical together
with a nutritionally balanced, mildly reduced-calorie diet that contains no
more than about 30% of calories from fat. It is recommended that the diet be
rich in fruits and vegetables. You should evenly divide your daily intake of
fat, carbohydrates, and protein over 3 main meals.
Doses greater than 120 mg three
times a day have not been shown to provide an additional weight loss
A healthy eating plan will help
you lose weight while decreasing some of the possible gastrointestinal
effects you may experience while taking Xenical.
How long should I use Xenical ?
Because Xenical works by blocking
the absorption of dietary fat, it is likely that you will experience some
changes in bowel habits. These changes may include oily spotting, gas with
discharge, urgent need to go to the bathroom, oily or fatty stools, an oily
discharge, increased number of bowel movements, and inability to control
These incidences will increase if
more fatty food is taken. You may reduce it be reinforce your diet by
choosing low fat food or reducing portion of fat in your food. This may help
you monitor and regulate your fat intake.
These bowel changes are a natural
effect of blocking the fat from being absorbed and indicate that Xenical is
working. These symptoms are often temporary and may lessen or disappear as
you continue treatment and keep to your recommended diet of meals containing
no more than about 30% fat.
If you are
concerned about these or any other side effects you experience while taking
Xenical, talk to your doctor or pharmacist.
What lifestyle changes should
I consider when taking Xenical ?
You must use Xenical with a
recommended mildly reduced-calorie diet. You should also follow a program of
regular physical activity, such as walking. However, before you undertake
any activity or exercise program, be sure to speak with your doctor or
While you are taking Xenical
* Tell all doctors, dentists and
pharmacists who are treating you that you are taking Xenical.
* Tell your pharmacist or doctor
if you become pregnant while taking Xenical.
* Do not give your Xenical to
anyone else, even they have the same condition as you.
* Do not take any other medicines
without first consulting a pharmacist or doctor.
How to store Xenical
The blister packs of Xenical
should be stored at temperature below 25oC and kept in a dry
place. Do no take the capsules after the expiry date shown on the pack. Keep
this medicine out of reach of children.