What is this medicine used for ?
ZYRTEC-D is used for the treatment of symptoms associated with seasonal and
perennial allergic rhinitis such as nasal congestion ( blocked nose ),
sneezing, rhinorrhea ( runny nose ), nasal and ocular pruritus ( itching of
the nose and eyes ).
How much and often should you
use this medicine ?
Adults and children aged 12 years
and older : one tablet twice daily ( morning and evening ), with or without
food. The tablets should be swallowed whole with some liquid and should not
be chewed or crushed.
When should you not take this
• if you are hypersensitive (
allergic ) to one of its ingredients, to ephedrine or any other piperazine.
• if you have severe high blood
pressure or severe heart disease.
• if you are taking
• if you are suffering from
severe kidney disease, uncontrolled hyperthroidism, severe arrhythmias (
irregular heart rate ), pheochromocytoma, elevated intraocular pressure or
• during treatment with monoamine
oxidase inhibitors ( MAOI) and also for 2 weeks after heir discontinuation
• if you have a history of stroke
• if you are at high risk of
developing haemorrhagic stroke
• if you have hereditary problems
of galactose intolerance, the Lapp lactase deficiency or glucose-galactose
• if you are pregnant or
• not in children under 12 years
What other medicine or food
should be avoided whilst taking this medicine ?
Please do not take Zyrtec-D if
you are taking the following medications :
• monoamine oxidase inhibitors (
MAOIs ) an for at least 15 days after stopping this medication
• beta-adrenergic blockers
• methyldopa, guanethidine,
• antacids, proton pump
• halogenated anaesthetic agents
Please do not take Zyrtec-D if
you are taking allergy skin tests. An appropriate wash-out period is
required before performing such tests.
Signs & symptoms of overdose
Diarrhoea, dizziness, fatigue,
headache, malaise, mydriasis (pupil dilation), urinary retention,
tachycardia, cardiac arrhythmia, arterial hypertension, signs of CNS
depression ( sedation, apnoea, unconsciousness, cyanosis and cardiovascular
collapse) or stimulation ( insomnia, hallucinations, tremor, seizures) which
could be fatal.
What to do when you have taken
more than the recommended dose ?
In cases of overdose, please seek
Precautions to take when
taking this medicine
Do not exceed the recommended
dose if driving a car or operating potentially dangerous machinery. Do not
drive if you feel drowsy or dizzy.
Zyrtec-D should be used with
caution in the elderly.
When should you consult your
Please consult your doctor before
taking Zyrtec-D if :
1) you have any of the following
medical conditions :
• diabetes mellitus
• arterial hypertension
• cardiac arrhythmia
• ischemic heart disease
• moderate renal or hepatic
• prostatic hypertrophy
• bladder outflow obstruction
• inflammatory bowel disease (
risk of hypercoagulability )
2) you are taking any of the
following medications :
• sympathomimetic drugs such as
decongestants, appetite suppressants, psychostimulants such as amphetamines
( combined effects on the cardiovascular system ),
• tricyclic antidepressants,
• antihypertensive drugs (
reduction of antihypertensive effects),
• alcohol or other CNS
depressants ( enhanced CNS depressiona nd impaired performance),
• digitalis ( risk of cardiac
• Vasoconstrictors such as
bromocriptine, pergolide, lisuride, carbergoline, ergotamine ( increased
risk of haemorrhagic stroke)
• NSAIDs (if you have high blood
pressure and taking NSAIDs at the same -- increase blood pressure )